Gruppo Pagliaro

CENTRO DI RICERCA
Dipartimento di Scienze CLiniche e Biologiche, Universita’ di Torino, italia
Group Leader
Pagliaro Pasquale
pasquale.pagliaro@unito.it
Componenti
 
 
Stefano Geuna
Penna Claudia
Perrelli Maria Giulia
Stefania Raimondo
Francesca Moro
Interessi Scentifici
Meccanismi di cardioprotezione e riparazione del danno ischemico, meccanismo di differenziamento e di sopravvivenza cellulare.
 
 
Expertise
 
Studi con modelli cellulari (cellule staminali mesenchimali estratte da midollo osseo e su line cellular H9c2), impiego di preparati ex vivo (cuore isolato), biologia molecolare, protocolli di separazione di frazioni cellulari.
Pubblicazioni  caratterizzanti 
 
Penna C, Perrelli MG, Raimondo S, Tullio F, Merlino A, Moro F, Geuna S, Mancardi D, Pagliaro P. Postconditioning induces an anti-apoptotic effect and preserves mitochondrial integrity in isolated rat hearts. Biochim Biophys Acta. 2009 Jul;1787(7):794-801.
Penna C, Raimondo S, Ronchi G, Rastaldo R, Mancardi D, Cappello S, Losano G, Geuna S, Pagliaro P Early homing of adult mesenchymal stem cells in normal and infarcted isolated beating hearts. J Cell Mol Med. 2008 Apr;12(2):507-21.
Pasquinelli G, Orrico C, Foroni L, Bonafè F, Carboni M, Guarnieri C, Raimondo S, Penna C, Geuna S, Pagliaro P, Freyrie A, Stella A, Caldarera CM, Muscari C. Mesenchymal stem cell interaction with a non-woven hyaluronan-based scaffold suitable for tissue repair. J Anat. 2008 Nov;213(5):520-30.
Gallo MP, Ramella R, Alloatti G, Penna C, Pagliaro P, Marcantoni A, Bonafé F, Losano G, Levi R. Limited plasticity of mesenchymal stem cells cocultured with adult cardiomyocytes. J Cell Biochem. 2007 Jan 1;100(1):86-99.
Raimondo S, Penna C, Pagliaro P, Geuna S.Morphological characterization of GFP stably transfected adult mesenchymal bone marrow stem cells. J Anat. 2006 Jan;208(1):3-12.
Strumentazioni disponibili
 
Incubatori per colture cellulari, sistemi di perfusione per cuore isolato, microscopio confocale ZEISS LSM-510, microscopio elettronico JOL 10-10 Optima LE-80K, ultracentrifughe, camera ipossica, sistemi per biologia molecolare western blotting.

 
 
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